One thing that drives me crazy lately is the fact that every single time a company comes out with a new USB audio interface, one of the first things that people start complaining about is the lack of USB 3.0 support.
For some reason people automatically assume USB 3.0 offers some kind of benefits over USB 2.0 when it comes to audio interfaces but that is simply not true.
If anything you’re going to encounter more problems using USB 3.0 because it’s less compatible with pretty much everything.
Focusrite support has this article, USB 2.0 vs USB 3.0, explaining why adding USB 3.0 to audio interfaces is pretty much pointless.
First and foremost, USB 3.0 offers greater bandwidth. It does not lower latency. Lots of people seem to think because USB 3.0 is faster that it will lower latency, but that is a myth.
The main benefit with USB 3.0 is increased bandwidth.
However that is fool’s gold as well because USB 2.0 has enough bandwidth to handle running audio interfaces with 18 inputs and 20 outputs simultaneously, so in most cases the increased bandwidth serves no purpose.
Then there’s the point of compatibility. The problem with USB 3.0 devices is that they require using a USB 3.0 port, and a number of computers still don’t support them. However, you can use a USB 2.0 device with a 3.0 port in most cases without problems so there isn’t the same compatibility issues with 2.0 like there is with 3.0.
Given all these factors, USB 3.0 serves no purpose on audio interfaces whatsoever unless you need more bandwidth to run over 3 dozen inputs and outputs at the same time.
By and large it’s the quality of the USB drivers that make the most difference, not the version of USB used.